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                    "reference": "urn:uuid:0da8dcb7-22dc-474c-8de6-a7ca89336ab0"
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                  "status": "generated",
                  "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h3>Chemistry</h3><table class=\"hl7__eu__lab__report\"><thead><tr><th>Test</th><th>23-JUN-2022</th><th>Reference&#xA0;Range</th><th>Unit</th></tr></thead><tbody><tr><td>Glucose [Mass/volume] in Serum or Plasma</td><td>76.5</td><td>70 - 100</td><td>mg/dL</td></tr><tr><td>Urea nitrogen [Mass/volume] in Serum or Plasma</td><td>7.4</td><td>7 - 20</td><td>mg/dL</td></tr><tr><td>Creatinine [Mass/volume] in Serum or Plasma</td><td><strong>1.9 H</strong></td><td>0.6 - 1.2</td><td>mg/dL</td></tr><tr><td>Calcium [Mass/volume] in Serum or Plasma</td><td>9.5</td><td>8.5 - 10.5</td><td>mg/dL</td></tr><tr><td>Sodium [Moles/volume] in Serum or Plasma</td><td>139.8</td><td>135 - 145</td><td>mmol/L</td></tr><tr><td>Potassium [Moles/volume] in Serum or Plasma</td><td>4.1</td><td>3.5 - 5.1</td><td>mmol/L</td></tr><tr><td>Chloride [Moles/volume] in Serum or Plasma</td><td><strong>107.6 H</strong></td><td>98 - 107</td><td>mmol/L</td></tr><tr><td>Carbon dioxide, total [Moles/volume] in Serum or Plasma</td><td>23.1</td><td>22 - 32</td><td>mmol/L</td></tr><tr><td>Ketones [Presence] in Urine by Test strip</td><td>Urine ketone test = ++</td><td></td><td></td></tr><tr><td>Hemoglobin A1c/Hemoglobin.total in Blood</td><td><strong>3.3 L</strong></td><td>4.0 - 5.6</td><td>%</td></tr><tr><td>Glucose [Mass/volume] in Blood</td><td>76.5</td><td>70 - 100</td><td>mg/dL</td></tr><tr><td>Urea nitrogen [Mass/volume] in Blood</td><td>7.4</td><td>7 - 20</td><td>mg/dL</td></tr><tr><td>Creatinine [Mass/volume] in Blood</td><td><strong>3.8 H</strong></td><td>0.6 - 1.2</td><td>mg/dL</td></tr><tr><td>Calcium [Mass/volume] in Blood</td><td>9.5</td><td>8.5 - 10.5</td><td>mg/dL</td></tr><tr><td>Sodium [Moles/volume] in Blood</td><td>139.8</td><td>135 - 145</td><td>mmol/L</td></tr><tr><td>Potassium [Moles/volume] in Blood</td><td>4.1</td><td>3.5 - 5.1</td><td>mmol/L</td></tr><tr><td>Chloride [Moles/volume] in Blood</td><td><strong>107.6 H</strong></td><td>98 - 107</td><td>mmol/L</td></tr><tr><td>Carbon dioxide, total [Moles/volume] in Blood</td><td>23.1</td><td>22 - 29</td><td>mmol/L</td></tr><tr><td>Cholesterol [Mass/volume] in Serum or Plasma</td><td>186.1</td><td>125 - 200</td><td>mg/dL</td></tr><tr><td>Triglyceride [Mass/volume] in Serum or Plasma</td><td>102.3</td><td>0 - 150</td><td>mg/dL</td></tr><tr><td>Cholesterol in LDL [Mass/volume] in Serum or Plasma by Direct assay</td><td><strong>104.5 H</strong></td><td>0 - 100</td><td>mg/dL</td></tr><tr><td>Cholesterol in HDL [Mass/volume] in Serum or Plasma</td><td><strong>61.2 H</strong></td><td>40 - 60</td><td>mg/dL</td></tr><tr><td>Microalbumin/Creatinine [Mass Ratio] in Urine</td><td><strong>39.6 H</strong></td><td>0 - 30</td><td>mg/g</td></tr></tbody></table></div>"
                },
                "title": "Chemistry"
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                  "status": "generated",
                  "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h3>Urinalysis</h3><table class=\"hl7__eu__lab__report\"><thead><tr><th>Test</th><th>23-JUN-2022</th><th>Reference&#xA0;Range</th><th>Unit</th></tr></thead><tbody><tr><td>Glucose [Mass/volume] in Urine by Test strip</td><td>0.8</td><td>0 - 5</td><td>mg/dL</td></tr><tr><td>Glucose [Presence] in Urine by Test strip</td><td>Urine glucose test = ++</td><td></td><td></td></tr><tr><td>Bilirubin.total [Mass/volume] in Urine by Test strip</td><td><strong>1.2 H</strong></td><td>0 - 1</td><td>mg/dL</td></tr><tr><td>Bilirubin.total [Presence] in Urine by Test strip</td><td>Finding of bilirubin in urine</td><td></td><td></td></tr><tr><td>Ketones [Mass/volume] in Urine by Test strip</td><td>6.7</td><td>0 - 20</td><td>mg/dL</td></tr><tr><td>Specific gravity of Urine by Test strip</td><td><strong>1.0 L</strong></td><td>1.005 - 1.030</td><td>{nominal}</td></tr><tr><td>pH of Urine by Test strip</td><td>6.8</td><td>5.0 - 8.0</td><td>pH</td></tr><tr><td>Protein [Mass/volume] in Urine by Test strip</td><td><strong>314.7 H</strong></td><td>0 - 20</td><td>mg/dL</td></tr><tr><td>Protein [Presence] in Urine by Test strip</td><td>Urine protein test = ++</td><td></td><td></td></tr><tr><td>Nitrite [Presence] in Urine by Test strip</td><td>Urine nitrite negative</td><td></td><td></td></tr><tr><td>Hemoglobin [Presence] in Urine by Test strip</td><td>Urine blood test = negative</td><td></td><td></td></tr><tr><td>Leukocyte esterase [Presence] in Urine by Test strip</td><td>Urine leukocyte test negative</td><td></td><td></td></tr></tbody></table></div>"
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                "entry": [
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                  "status": "generated",
                  "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h3>Specimen information</h3><table class=\"hl7__eu__lab__report\"><thead><tr><th>Test</th><th>23-JUN-2022</th><th>Specimen</th><th></th></tr></thead><tbody><tr><td>Appearance of Urine</td><td>Cloudy urine</td><td>Urine</td><td></td></tr><tr><td>Odor of Urine</td><td>Urine smell ammoniacal</td><td>Urine</td><td></td></tr><tr><td>Clarity of Urine</td><td>Translucent</td><td>Urine</td><td></td></tr><tr><td>Color of Urine</td><td>Brown color</td><td>Urine</td><td></td></tr></tbody></table></div>"
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              "status": "generated",
              "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h3>Annotation</h3><table class=\"hl7__eu__lab__report\"><tr><th>Conclusion and Recommendations based on this report and previous findings known to us</th></tr><tr><td>The patient shows significantly elevated creatinine, proteinuria, microalbuminuria, and low urine specific gravity, suggesting impaired renal function, possibly chronic kidney disease. Urine is abnormal in appearance and color, with bilirubin and ketones present. LDL cholesterol is mildly elevated. HbA1c is low, indicating no evidence of chronic hyperglycemia. Recommend nephrology evaluation and further assessment for underlying renal pathology and possible hepatic involvement.</td></tr></table></div>"
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              "code": "HTEST"
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            {
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              "system": "https://synderai.net/fhir/CodeSystem/tags",
              "code": "synthetic",
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            "system": "http://local.setting.eu/identifier",
            "value": "8e2c4509-b594-9ec4-42db-847eccf28678"
          }
        ],
        "name": [
          {
            "given": [
              "Tom"
            ],
            "family": "Hayward",
            "text": "Tom Hayward"
          }
        ],
        "address": [
          {
            "line": [
              "391 Dean locks"
            ],
            "use": "home",
            "type": "physical",
            "postalCode": "M1",
            "city": "Manchester",
            "country": "United Kingdom"
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        ],
        "telecom": [
          {
            "system": "phone",
            "value": "+44(0)808 1570544"
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        ],
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            "extension": [
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                "url": "code",
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                  ]
                }
              }
            ],
            "url": "http://hl7.org/fhir/StructureDefinition/patient-nationality"
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        ],
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        "gender": "male",
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      "fullUrl": "urn:uuid:19b88032-cd6b-4355-b9e8-4ba6f1eaefa9",
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        "resourceType": "ServiceRequest",
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          "profile": [
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        "identifier": [
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            "value": "caa2210d-d8fd-4181-babb-be5be373b295"
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        "specimen": [
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          {
            "reference": "urn:uuid:540bb960-c7d5-493e-a398-12c3b1337bf9"
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          {
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            ]
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          {
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            ]
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          {
            "coding": [
              {
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                "display": "Proteinuria due to type 2 diabetes mellitus"
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          {
            "coding": [
              {
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                "system": "http://snomed.info/sct",
                "display": "Ischemic heart disease"
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            ]
          },
          {
            "coding": [
              {
                "code": "55822004",
                "system": "http://snomed.info/sct",
                "display": "Hyperlipidemia"
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            ]
          },
          {
            "coding": [
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                "system": "http://snomed.info/sct",
                "display": "Chronic kidney disease stage 2"
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          {
            "coding": [
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                "code": "90781000119102",
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                "display": "Microalbuminuria due to type 2 diabetes mellitus"
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          },
          {
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          {
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                "system": "http://snomed.info/sct",
                "display": "Chronic kidney disease stage 1"
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            ]
          },
          {
            "coding": [
              {
                "code": "1551000119108",
                "system": "http://snomed.info/sct",
                "display": "Nonproliferative retinopathy due to type 2 diabetes mellitus"
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            ]
          },
          {
            "coding": [
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                "system": "http://snomed.info/sct",
                "display": "Retinopathy due to type 2 diabetes mellitus"
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            ]
          },
          {
            "coding": [
              {
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                "system": "http://snomed.info/sct",
                "display": "Anemia"
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            ]
          },
          {
            "coding": [
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                "code": "80394007",
                "system": "http://snomed.info/sct",
                "display": "Hyperglycemia"
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            ]
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          {
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              {
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                "system": "http://snomed.info/sct",
                "display": "Metabolic syndrome X"
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            ]
          },
          {
            "coding": [
              {
                "code": "302870006",
                "system": "http://snomed.info/sct",
                "display": "Hypertriglyceridemia"
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            ]
          },
          {
            "coding": [
              {
                "code": "44054006",
                "system": "http://snomed.info/sct",
                "display": "Type 2 diabetes mellitus"
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            ]
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          {
            "coding": [
              {
                "code": "59621000",
                "system": "http://snomed.info/sct",
                "display": "Essential hypertension"
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            ]
          }
        ],
        "text": {
          "status": "empty",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\">intentionally left empty / not meaningful</div>"
        },
        "status": "active",
        "intent": "order",
        "code": {
          "coding": [
            {
              "code": "108252007",
              "system": "http://snomed.info/sct",
              "display": "Laboratory procedure"
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          ]
        },
        "subject": {
          "reference": "urn:uuid:75518a8f-5bc5-4674-9ac9-3f0111637b68",
          "display": "Tom Hayward"
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        "id": "02824c45-9109-4e6d-959e-b0a460308e7a",
        "meta": {
          "profile": [
            "http://hl7.eu/fhir/base/StructureDefinition/practitionerRole-eu"
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        },
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          "status": "generated",
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            "postalCode": "M3 3",
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        ],
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        "name": "Cornbrook Medical Practice"
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    {
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              "display": "Acellular blood (serum or plasma) specimen"
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    {
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            "http://hl7.eu/fhir/laboratory/StructureDefinition/Specimen-eu-lab"
          ]
        },
        "collection": {
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        "text": {
          "status": "generated",
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        },
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    {
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        },
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        },
        "type": {
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            {
              "code": "258580003",
              "system": "http://snomed.info/sct",
              "display": "Whole blood specimen (specimen)"
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          ]
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      }
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    {
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              "system": "http://loinc.org",
              "display": "Glucose [Mass/volume] in Serum or Plasma"
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          "text": "Glucose [Mass/volume] in Serum or Plasma"
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          "unit": "mg/dL",
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              "value": 100,
              "code": "mg/dL",
              "system": "http://unitsofmeasure.org"
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          }
        ],
        "text": {
          "status": "generated",
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    {
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              "code": "3094-0",
              "system": "http://loinc.org",
              "display": "Urea nitrogen [Mass/volume] in Serum or Plasma"
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          "text": "Urea nitrogen [Mass/volume] in Serum or Plasma"
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              "code": "mg/dL",
              "system": "http://unitsofmeasure.org"
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              "display": "Creatinine [Mass/volume] in Serum or Plasma"
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          ],
          "text": "Creatinine [Mass/volume] in Serum or Plasma"
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                "display": "High"
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        },
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    {
      "fullUrl": "urn:uuid:80bbb2f6-5c01-4a41-9a46-eb9a3d42ae8e",
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        "category": [
          {
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                "code": "laboratory",
                "system": "http://terminology.hl7.org/CodeSystem/observation-category"
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        ],
        "performer": [
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        ],
        "code": {
          "coding": [
            {
              "code": "17861-6",
              "system": "http://loinc.org",
              "display": "Calcium [Mass/volume] in Serum or Plasma"
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          ],
          "text": "Calcium [Mass/volume] in Serum or Plasma"
        },
        "valueQuantity": {
          "system": "http://unitsofmeasure.org",
          "value": 9.5,
          "unit": "mg/dL",
          "code": "mg/dL"
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        "referenceRange": [
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              "code": "mg/dL",
              "system": "http://unitsofmeasure.org"
            },
            "high": {
              "value": 10.5,
              "code": "mg/dL",
              "system": "http://unitsofmeasure.org"
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          }
        ],
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><table class=\"hl7__eu__lab__report\"><tr><th>Test</th><th>23-Jun-2022</th><th>Reference&#xA0;Range</th><th>Unit</th></tr><tr><td>Calcium [Mass/volume] in Serum or Plasma</td><td>9.5</td><td>8.5 - 10.5</td><td></td><td>mg/dL</td></tr></table></div>"
        },
        "status": "final",
        "subject": {
          "reference": "urn:uuid:75518a8f-5bc5-4674-9ac9-3f0111637b68",
          "display": "Tom Hayward"
        },
        "effectiveDateTime": "2022-06-23T06:17:44Z",
        "specimen": {
          "reference": "urn:uuid:75492f39-d06e-4676-8c55-730a561497a0"
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      }
    },
    {
      "fullUrl": "urn:uuid:50c3d3ca-4826-4612-8977-180207741c69",
      "resource": {
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        "meta": {
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        },
        "category": [
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        ],
        "performer": [
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        "code": {
          "coding": [
            {
              "code": "2951-2",
              "system": "http://loinc.org",
              "display": "Sodium [Moles/volume] in Serum or Plasma"
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          ],
          "text": "Sodium [Moles/volume] in Serum or Plasma"
        },
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          "value": 139.8,
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            "high": {
              "value": 145,
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        ],
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            {
              "code": "2823-3",
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              "display": "Potassium [Moles/volume] in Serum or Plasma"
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          ],
          "text": "Potassium [Moles/volume] in Serum or Plasma"
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          "value": 4.1,
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            "high": {
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        ],
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              "code": "2075-0",
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              "display": "Chloride [Moles/volume] in Serum or Plasma"
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        "category": [
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              "code": "2028-9",
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              "display": "Carbon dioxide, total [Moles/volume] in Serum or Plasma"
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        "valueQuantity": {
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          "value": 23.1,
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        "referenceRange": [
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            "high": {
              "value": 32,
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        },
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        "code": {
          "coding": [
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              "code": "5767-9",
              "system": "http://loinc.org",
              "display": "Appearance of Urine"
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          ],
          "text": "Appearance of Urine"
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        "code": {
          "coding": [
            {
              "code": "34533-0",
              "system": "http://loinc.org",
              "display": "Odor of Urine"
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          ],
          "text": "Odor of Urine"
        },
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        },
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        "valueCodeableConcept": {
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        "category": [
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        "code": {
          "coding": [
            {
              "code": "32167-9",
              "system": "http://loinc.org",
              "display": "Clarity of Urine"
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          ],
          "text": "Clarity of Urine"
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        "text": {
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        },
        "status": "final",
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        "valueCodeableConcept": {
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              "display": "Translucent"
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        "category": [
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        "code": {
          "coding": [
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              "code": "5778-6",
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              "display": "Color of Urine"
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          ],
          "text": "Color of Urine"
        },
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        },
        "status": "final",
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        "valueCodeableConcept": {
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        "category": [
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        ],
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        ],
        "code": {
          "coding": [
            {
              "code": "5792-7",
              "system": "http://loinc.org",
              "display": "Glucose [Mass/volume] in Urine by Test strip"
            }
          ],
          "text": "Glucose [Mass/volume] in Urine by Test strip"
        },
        "valueQuantity": {
          "system": "http://unitsofmeasure.org",
          "value": 0.8,
          "unit": "mg/dL",
          "code": "mg/dL"
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        "referenceRange": [
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              "system": "http://unitsofmeasure.org"
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          }
        ],
        "text": {
          "status": "generated",
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        },
        "status": "final",
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        "effectiveDateTime": "2022-06-23T06:17:44Z",
        "specimen": {
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        "category": [
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        "code": {
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              "code": "25428-4",
              "system": "http://loinc.org",
              "display": "Glucose [Presence] in Urine by Test strip"
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          ],
          "text": "Glucose [Presence] in Urine by Test strip"
        },
        "text": {
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          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><table class=\"hl7__eu__lab__report\"><tr><th>Test</th><th>23-Jun-2022</th><th>Reference&#xA0;Range</th><th>Unit</th></tr><tr><td>Glucose [Presence] in Urine by Test strip</td><td>Urine glucose test = ++</td></tr></table></div>"
        },
        "status": "final",
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          "display": "Tom Hayward"
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        "effectiveDateTime": "2022-06-23T06:17:44Z",
        "valueCodeableConcept": {
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              "display": "Urine glucose test = ++"
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        "code": {
          "coding": [
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              "code": "20505-4",
              "system": "http://loinc.org",
              "display": "Bilirubin.total [Mass/volume] in Urine by Test strip"
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          ],
          "text": "Bilirubin.total [Mass/volume] in Urine by Test strip"
        },
        "valueQuantity": {
          "system": "http://unitsofmeasure.org",
          "value": 1.2,
          "unit": "mg/dL",
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                "display": "High"
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            ]
          }
        ],
        "text": {
          "status": "generated",
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        },
        "status": "final",
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          "text": "Bilirubin.total [Presence] in Urine by Test strip"
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              "code": "5797-6",
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              "display": "Ketones [Mass/volume] in Urine by Test strip"
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          "text": "Ketones [Mass/volume] in Urine by Test strip"
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              "code": "2514-8",
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              "display": "Ketones [Presence] in Urine by Test strip"
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          "text": "Ketones [Presence] in Urine by Test strip"
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          ],
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              "code": "5803-2",
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              "display": "Protein [Mass/volume] in Urine by Test strip"
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          "text": "Protein [Mass/volume] in Urine by Test strip"
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          "text": "Protein [Presence] in Urine by Test strip"
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        "code": {
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              "display": "Nitrite [Presence] in Urine by Test strip"
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              "code": "5794-3",
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              "display": "Hemoglobin [Presence] in Urine by Test strip"
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          "text": "Hemoglobin [Presence] in Urine by Test strip"
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              "code": "5799-2",
              "system": "http://loinc.org",
              "display": "Leukocyte esterase [Presence] in Urine by Test strip"
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          ],
          "text": "Leukocyte esterase [Presence] in Urine by Test strip"
        },
        "text": {
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              "code": "4548-4",
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              "display": "Hemoglobin A1c/Hemoglobin.total in Blood"
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          ],
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        "valueQuantity": {
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          "value": 3.3,
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              "code": "2339-0",
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              "display": "Glucose [Mass/volume] in Blood"
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          ],
          "text": "Glucose [Mass/volume] in Blood"
        },
        "valueQuantity": {
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              "code": "6299-2",
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              "display": "Urea nitrogen [Mass/volume] in Blood"
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          ],
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              "display": "Creatinine [Mass/volume] in Blood"
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          "text": "Creatinine [Mass/volume] in Blood"
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        "valueQuantity": {
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              "display": "Calcium [Mass/volume] in Blood"
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              "display": "Sodium [Moles/volume] in Blood"
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          "value": 139.8,
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              "value": 145,
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              "display": "Potassium [Moles/volume] in Blood"
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          ],
          "text": "Potassium [Moles/volume] in Blood"
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          "value": 4.1,
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              "display": "Chloride [Moles/volume] in Blood"
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          ],
          "text": "Chloride [Moles/volume] in Blood"
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        "valueQuantity": {
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          "value": 107.6,
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        "code": {
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              "code": "20565-8",
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              "display": "Carbon dioxide, total [Moles/volume] in Blood"
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          ],
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          "value": 23.1,
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            "high": {
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        "code": {
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              "code": "2093-3",
              "system": "http://loinc.org",
              "display": "Cholesterol [Mass/volume] in Serum or Plasma"
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          ],
          "text": "Cholesterol [Mass/volume] in Serum or Plasma"
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        "valueQuantity": {
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            "high": {
              "value": 200,
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        ],
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        "code": {
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              "code": "2571-8",
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              "display": "Triglyceride [Mass/volume] in Serum or Plasma"
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              "display": "Cholesterol in LDL [Mass/volume] in Serum or Plasma by Direct assay"
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          "text": "Cholesterol in LDL [Mass/volume] in Serum or Plasma by Direct assay"
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              "display": "Microalbumin/Creatinine [Mass Ratio] in Urine"
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          "text": "Microalbumin/Creatinine [Mass Ratio] in Urine"
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          "value": 39.6,
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            "type": "manufacturer-name"
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          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\">SYNDERAI Synthetic Generator v5.0</div>"
        },
        "status": "active",
        "distinctIdentifier": "synderai-generator-50",
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              "system": "http://terminology.hl7.org/CodeSystem/v3-DataOperation",
              "display": "create"
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          ],
          "text": "Synthetic Example Data Generation"
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        "policy": [
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        "agent": [
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                "display": "training"
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            ],
            "text": "Interoperability Testing and Training (non-clinical use)"
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        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\">Provenance for SYNDERAI Synthetic Example Data Resource</div>"
        },
        "recorded": "2022-06-23T08:17:44Z"
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        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\">Laboratory Role Id: d8ff9792-87ba-4275-b7e6-40eb2584ee94</div>"
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        "practitioner": {
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              "Boulevard du Jardin Botanique 32"
            ],
            "postalCode": "1000",
            "city": "Brussels",
            "country": "Belgium"
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        ],
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\">Laboratory: Laboratoire Central Européenne, 1000 Brussels, Belgium</div>"
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  ],
  "type": "document",
  "timestamp": "2022-06-23T08:17:44Z"
}
