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                  "status": "generated",
                  "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h3>Chemistry</h3><table class=\"hl7__eu__lab__report\"><thead><tr><th>Test</th><th>29-SEP-2022</th><th>Reference&#xA0;Range</th><th>Unit</th></tr></thead><tbody><tr><td>Glucose [Mass/volume] in Serum or Plasma</td><td>78.3</td><td>70 - 100</td><td>mg/dL</td></tr><tr><td>Urea nitrogen [Mass/volume] in Serum or Plasma</td><td>15.9</td><td>7 - 20</td><td>mg/dL</td></tr><tr><td>Creatinine [Mass/volume] in Serum or Plasma</td><td><strong>2.0 H</strong></td><td>0.6 - 1.2</td><td>mg/dL</td></tr><tr><td>Calcium [Mass/volume] in Serum or Plasma</td><td>8.7</td><td>8.5 - 10.5</td><td>mg/dL</td></tr><tr><td>Sodium [Moles/volume] in Serum or Plasma</td><td>142.2</td><td>135 - 145</td><td>mmol/L</td></tr><tr><td>Potassium [Moles/volume] in Serum or Plasma</td><td>4.9</td><td>3.5 - 5.1</td><td>mmol/L</td></tr><tr><td>Chloride [Moles/volume] in Serum or Plasma</td><td>101.4</td><td>98 - 107</td><td>mmol/L</td></tr><tr><td>Carbon dioxide, total [Moles/volume] in Serum or Plasma</td><td>28.6</td><td>22 - 32</td><td>mmol/L</td></tr><tr><td>Ketones [Presence] in Urine by Test strip</td><td>Urine ketone test = ++</td><td></td><td></td></tr><tr><td>Hemoglobin A1c/Hemoglobin.total in Blood</td><td><strong>3.3 L</strong></td><td>4.0 - 5.6</td><td>%</td></tr><tr><td>Glucose [Mass/volume] in Blood</td><td>78.3</td><td>70 - 100</td><td>mg/dL</td></tr><tr><td>Urea nitrogen [Mass/volume] in Blood</td><td>15.9</td><td>7 - 20</td><td>mg/dL</td></tr><tr><td>Creatinine [Mass/volume] in Blood</td><td><strong>3.7 H</strong></td><td>0.6 - 1.2</td><td>mg/dL</td></tr><tr><td>Calcium [Mass/volume] in Blood</td><td>8.7</td><td>8.5 - 10.5</td><td>mg/dL</td></tr><tr><td>Sodium [Moles/volume] in Blood</td><td>142.2</td><td>135 - 145</td><td>mmol/L</td></tr><tr><td>Potassium [Moles/volume] in Blood</td><td>4.9</td><td>3.5 - 5.1</td><td>mmol/L</td></tr><tr><td>Chloride [Moles/volume] in Blood</td><td>101.4</td><td>98 - 107</td><td>mmol/L</td></tr><tr><td>Carbon dioxide, total [Moles/volume] in Blood</td><td>28.6</td><td>22 - 29</td><td>mmol/L</td></tr><tr><td>Cholesterol [Mass/volume] in Serum or Plasma</td><td>159.5</td><td>125 - 200</td><td>mg/dL</td></tr><tr><td>Triglyceride [Mass/volume] in Serum or Plasma</td><td>120.5</td><td>0 - 150</td><td>mg/dL</td></tr><tr><td>Cholesterol in LDL [Mass/volume] in Serum or Plasma by Direct assay</td><td>73.7</td><td>0 - 100</td><td>mg/dL</td></tr><tr><td>Cholesterol in HDL [Mass/volume] in Serum or Plasma</td><td><strong>61.7 H</strong></td><td>40 - 60</td><td>mg/dL</td></tr><tr><td>Microalbumin/Creatinine [Mass Ratio] in Urine</td><td><strong>177.6 H</strong></td><td>0 - 30</td><td>mg/g</td></tr></tbody></table></div>"
                },
                "title": "Chemistry"
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                  "status": "generated",
                  "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h3>Urinalysis</h3><table class=\"hl7__eu__lab__report\"><thead><tr><th>Test</th><th>29-SEP-2022</th><th>Reference&#xA0;Range</th><th>Unit</th></tr></thead><tbody><tr><td>Glucose [Mass/volume] in Urine by Test strip</td><td>2.1</td><td>0 - 5</td><td>mg/dL</td></tr><tr><td>Glucose [Presence] in Urine by Test strip</td><td>Urine glucose test = ++</td><td></td><td></td></tr><tr><td>Bilirubin.total [Mass/volume] in Urine by Test strip</td><td><strong>1.2 H</strong></td><td>0 - 1</td><td>mg/dL</td></tr><tr><td>Bilirubin.total [Presence] in Urine by Test strip</td><td>Finding of bilirubin in urine</td><td></td><td></td></tr><tr><td>Ketones [Mass/volume] in Urine by Test strip</td><td>4.4</td><td>0 - 20</td><td>mg/dL</td></tr><tr><td>Specific gravity of Urine by Test strip</td><td><strong>1.0 L</strong></td><td>1.005 - 1.030</td><td>{nominal}</td></tr><tr><td>pH of Urine by Test strip</td><td>5.6</td><td>5.0 - 8.0</td><td>pH</td></tr><tr><td>Protein [Mass/volume] in Urine by Test strip</td><td><strong>340.2 H</strong></td><td>0 - 20</td><td>mg/dL</td></tr><tr><td>Protein [Presence] in Urine by Test strip</td><td>Urine protein test = ++</td><td></td><td></td></tr><tr><td>Nitrite [Presence] in Urine by Test strip</td><td>Urine nitrite negative</td><td></td><td></td></tr><tr><td>Hemoglobin [Presence] in Urine by Test strip</td><td>Urine blood test = negative</td><td></td><td></td></tr><tr><td>Leukocyte esterase [Presence] in Urine by Test strip</td><td>Urine leukocyte test negative</td><td></td><td></td></tr></tbody></table></div>"
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                  "status": "generated",
                  "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h3>Specimen information</h3><table class=\"hl7__eu__lab__report\"><thead><tr><th>Test</th><th>29-SEP-2022</th><th>Specimen</th><th></th></tr></thead><tbody><tr><td>Appearance of Urine</td><td>Cloudy urine</td><td>Urine</td><td></td></tr><tr><td>Odor of Urine</td><td>Urine smell ammoniacal</td><td>Urine</td><td></td></tr><tr><td>Clarity of Urine</td><td>Translucent</td><td>Urine</td><td></td></tr><tr><td>Color of Urine</td><td>Brown color</td><td>Urine</td><td></td></tr></tbody></table></div>"
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              "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h3>Annotation</h3><table class=\"hl7__eu__lab__report\"><tr><th>Conclusion and Recommendations based on this report and previous findings known to us</th></tr><tr><td>The patient shows significantly elevated creatinine in both serum and blood, indicating impaired renal function. Urinalysis reveals marked proteinuria, elevated microalbumin/creatinine ratio, bilirubinuria, low specific gravity, and abnormal urine appearance, all supporting renal dysfunction, possibly nephrotic syndrome or advanced kidney disease. Blood glucose and HbA1c are low, excluding diabetes as a cause. Recommend urgent nephrology evaluation for further assessment and management.</td></tr></table></div>"
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            {
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              "code": "TRAIN"
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          "tag": [
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              "system": "https://synderai.net/fhir/CodeSystem/tags",
              "code": "synthetic",
              "display": "SYNDERAI Synthetic data"
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          ],
          "profile": [
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        "identifier": [
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            },
            "system": "http://ec.europa.eu/identifier/eci",
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          {
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                  "system": "http://terminology.hl7.org/CodeSystem/v2-0203"
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            "system": "http://local.setting.eu/identifier",
            "value": "8e2c4509-b594-9ec4-42db-847eccf28678"
          }
        ],
        "name": [
          {
            "given": [
              "Tom"
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            "family": "Hayward",
            "text": "Tom Hayward"
          }
        ],
        "address": [
          {
            "line": [
              "391 Dean locks"
            ],
            "use": "home",
            "type": "physical",
            "postalCode": "M1",
            "city": "Manchester",
            "country": "United Kingdom"
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        ],
        "telecom": [
          {
            "system": "phone",
            "value": "+44(0)808 1570544"
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            "extension": [
              {
                "url": "code",
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                  ]
                }
              }
            ],
            "url": "http://hl7.org/fhir/StructureDefinition/patient-nationality"
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        "gender": "male",
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        },
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          {
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          {
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          {
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            ]
          },
          {
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                "display": "Proteinuria due to type 2 diabetes mellitus"
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          {
            "coding": [
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                "display": "Ischemic heart disease"
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            ]
          },
          {
            "coding": [
              {
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                "system": "http://snomed.info/sct",
                "display": "Hyperlipidemia"
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            ]
          },
          {
            "coding": [
              {
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                "system": "http://snomed.info/sct",
                "display": "Chronic kidney disease stage 2"
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          },
          {
            "coding": [
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          {
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                "system": "http://snomed.info/sct",
                "display": "Disorder of kidney due to diabetes mellitus"
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            ]
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          {
            "coding": [
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                "system": "http://snomed.info/sct",
                "display": "Chronic kidney disease stage 1"
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            ]
          },
          {
            "coding": [
              {
                "code": "1551000119108",
                "system": "http://snomed.info/sct",
                "display": "Nonproliferative retinopathy due to type 2 diabetes mellitus"
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            ]
          },
          {
            "coding": [
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                "code": "422034002",
                "system": "http://snomed.info/sct",
                "display": "Retinopathy due to type 2 diabetes mellitus"
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            ]
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          {
            "coding": [
              {
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                "system": "http://snomed.info/sct",
                "display": "Anemia"
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            ]
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          {
            "coding": [
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                "code": "80394007",
                "system": "http://snomed.info/sct",
                "display": "Hyperglycemia"
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            ]
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          {
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                "display": "Metabolic syndrome X"
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            ]
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          {
            "coding": [
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                "code": "302870006",
                "system": "http://snomed.info/sct",
                "display": "Hypertriglyceridemia"
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            ]
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          {
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                "code": "44054006",
                "system": "http://snomed.info/sct",
                "display": "Type 2 diabetes mellitus"
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            ]
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          {
            "coding": [
              {
                "code": "59621000",
                "system": "http://snomed.info/sct",
                "display": "Essential hypertension"
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            ]
          }
        ],
        "text": {
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          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\">intentionally left empty / not meaningful</div>"
        },
        "status": "active",
        "intent": "order",
        "code": {
          "coding": [
            {
              "code": "108252007",
              "system": "http://snomed.info/sct",
              "display": "Laboratory procedure"
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        "subject": {
          "reference": "urn:uuid:ec764339-4b59-426b-a819-74de91bc2529",
          "display": "Tom Hayward"
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        "id": "cc437b6f-8f40-4a8c-9b30-f52d71166b16",
        "meta": {
          "profile": [
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        },
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          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\">Provider Role Id: cc437b6f-8f40-4a8c-9b30-f52d71166b16</div>"
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            "postalCode": "M3 3",
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    {
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        },
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        },
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    {
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        },
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              "system": "http://snomed.info/sct",
              "display": "Whole blood specimen (specimen)"
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          ]
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    {
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              "system": "http://loinc.org",
              "display": "Glucose [Mass/volume] in Serum or Plasma"
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          "text": "Glucose [Mass/volume] in Serum or Plasma"
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          "value": 78.3,
          "unit": "mg/dL",
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              "code": "mg/dL",
              "system": "http://unitsofmeasure.org"
            }
          }
        ],
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          "status": "generated",
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              "code": "3094-0",
              "system": "http://loinc.org",
              "display": "Urea nitrogen [Mass/volume] in Serum or Plasma"
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          ],
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              "display": "Creatinine [Mass/volume] in Serum or Plasma"
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          "text": "Creatinine [Mass/volume] in Serum or Plasma"
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          "value": 2,
          "unit": "mg/dL",
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                "display": "High"
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        "text": {
          "status": "generated",
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    {
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        "category": [
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            ]
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        ],
        "performer": [
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        "code": {
          "coding": [
            {
              "code": "17861-6",
              "system": "http://loinc.org",
              "display": "Calcium [Mass/volume] in Serum or Plasma"
            }
          ],
          "text": "Calcium [Mass/volume] in Serum or Plasma"
        },
        "valueQuantity": {
          "system": "http://unitsofmeasure.org",
          "value": 8.7,
          "unit": "mg/dL",
          "code": "mg/dL"
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        "referenceRange": [
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              "value": 8.5,
              "code": "mg/dL",
              "system": "http://unitsofmeasure.org"
            },
            "high": {
              "value": 10.5,
              "code": "mg/dL",
              "system": "http://unitsofmeasure.org"
            }
          }
        ],
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><table class=\"hl7__eu__lab__report\"><tr><th>Test</th><th>29-Sep-2022</th><th>Reference&#xA0;Range</th><th>Unit</th></tr><tr><td>Calcium [Mass/volume] in Serum or Plasma</td><td>8.7</td><td>8.5 - 10.5</td><td></td><td>mg/dL</td></tr></table></div>"
        },
        "status": "final",
        "subject": {
          "reference": "urn:uuid:ec764339-4b59-426b-a819-74de91bc2529",
          "display": "Tom Hayward"
        },
        "effectiveDateTime": "2022-09-29T06:17:44Z",
        "specimen": {
          "reference": "urn:uuid:b9042c80-6568-4cd3-bf9c-c829bad46f4d"
        }
      }
    },
    {
      "fullUrl": "urn:uuid:c6f669d9-6697-41bf-8872-4bdae6ed148b",
      "resource": {
        "resourceType": "Observation",
        "id": "c6f669d9-6697-41bf-8872-4bdae6ed148b",
        "meta": {
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        },
        "category": [
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                "code": "laboratory",
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            ]
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        ],
        "performer": [
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        ],
        "code": {
          "coding": [
            {
              "code": "2951-2",
              "system": "http://loinc.org",
              "display": "Sodium [Moles/volume] in Serum or Plasma"
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          ],
          "text": "Sodium [Moles/volume] in Serum or Plasma"
        },
        "valueQuantity": {
          "system": "http://unitsofmeasure.org",
          "value": 142.2,
          "unit": "mmol/L",
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              "code": "5770-3",
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              "display": "Bilirubin.total [Presence] in Urine by Test strip"
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          "text": "Bilirubin.total [Presence] in Urine by Test strip"
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        "code": {
          "coding": [
            {
              "code": "5797-6",
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              "display": "Ketones [Mass/volume] in Urine by Test strip"
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          ],
          "text": "Ketones [Mass/volume] in Urine by Test strip"
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        "valueQuantity": {
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              "code": "2514-8",
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              "display": "Ketones [Presence] in Urine by Test strip"
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          ],
          "text": "Ketones [Presence] in Urine by Test strip"
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        "code": {
          "coding": [
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              "code": "5811-5",
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              "display": "Specific gravity of Urine by Test strip"
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          "value": 1,
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          "coding": [
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              "code": "5803-2",
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              "code": "5804-0",
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              "display": "Protein [Mass/volume] in Urine by Test strip"
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          ],
          "text": "Protein [Mass/volume] in Urine by Test strip"
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          "value": 340.2,
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              "code": "20454-5",
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        "code": {
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              "code": "5802-4",
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              "display": "Nitrite [Presence] in Urine by Test strip"
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              "display": "Hemoglobin [Presence] in Urine by Test strip"
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          "text": "Hemoglobin [Presence] in Urine by Test strip"
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              "code": "5799-2",
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              "display": "Leukocyte esterase [Presence] in Urine by Test strip"
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          ],
          "text": "Leukocyte esterase [Presence] in Urine by Test strip"
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              "code": "4548-4",
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              "display": "Hemoglobin A1c/Hemoglobin.total in Blood"
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          ],
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          "value": 3.3,
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          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><table class=\"hl7__eu__lab__report\"><tr><th>Test</th><th>29-Sep-2022</th><th>Reference&#xA0;Range</th><th>Unit</th></tr><tr><td>Triglyceride [Mass/volume] in Serum or Plasma</td><td>120.5</td><td>0 - 150</td><td></td><td>mg/dL</td></tr></table></div>"
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              "system": "http://loinc.org",
              "display": "Cholesterol in LDL [Mass/volume] in Serum or Plasma by Direct assay"
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          "text": "Cholesterol in LDL [Mass/volume] in Serum or Plasma by Direct assay"
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        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><table class=\"hl7__eu__lab__report\"><tr><th>Test</th><th>29-Sep-2022</th><th>Reference&#xA0;Range</th><th>Unit</th></tr><tr><td>Cholesterol in LDL [Mass/volume] in Serum or Plasma by Direct assay</td><td>73.7</td><td>0 - 100</td><td></td><td>mg/dL</td></tr></table></div>"
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              "code": "2085-9",
              "system": "http://loinc.org",
              "display": "Cholesterol in HDL [Mass/volume] in Serum or Plasma"
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          ],
          "text": "Cholesterol in HDL [Mass/volume] in Serum or Plasma"
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        "valueQuantity": {
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          "status": "generated",
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        "id": "f19ceca0-fdec-42c2-968a-6cbd3a107ced",
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        "code": {
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              "code": "14959-1",
              "system": "http://loinc.org",
              "display": "Microalbumin/Creatinine [Mass Ratio] in Urine"
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          ],
          "text": "Microalbumin/Creatinine [Mass Ratio] in Urine"
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        "valueQuantity": {
          "system": "http://unitsofmeasure.org",
          "value": 177.6,
          "unit": "mg/g",
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                "system": "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
                "display": "High"
              }
            ]
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        ],
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><table class=\"hl7__eu__lab__report\"><tr><th>Test</th><th>29-Sep-2022</th><th>Reference&#xA0;Range</th><th>Unit</th></tr><tr><td>Microalbumin/Creatinine [Mass Ratio] in Urine</td><td>177.6</td><td>0 - 30</td><td>H</td><td>mg/g</td></tr></table></div>"
        },
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        "effectiveDateTime": "2022-09-29T06:17:44Z",
        "specimen": {
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    {
      "fullUrl": "urn:uuid:b2042fb1-11c2-48e7-8e2d-c075e257bc24",
      "resource": {
        "resourceType": "Device",
        "id": "b2042fb1-11c2-48e7-8e2d-c075e257bc24",
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            "type": "manufacturer-name"
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        "version": [
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            "value": "5.0"
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        ],
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\">SYNDERAI Synthetic Generator v5.0</div>"
        },
        "status": "active",
        "distinctIdentifier": "synderai-generator-50",
        "manufacturer": "SYNDERAI Project"
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    {
      "fullUrl": "urn:uuid:0baf0a1c-a584-423c-823d-804e891fc480",
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              "code": "CREATE",
              "system": "http://terminology.hl7.org/CodeSystem/v3-DataOperation",
              "display": "create"
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          ],
          "text": "Synthetic Example Data Generation"
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        "policy": [
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        "agent": [
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            "type": {
              "coding": [
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                  "code": "author",
                  "system": "http://terminology.hl7.org/CodeSystem/provenance-participant-type",
                  "display": "Author"
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              ],
              "text": "author"
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            "who": {
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        "reason": [
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                "code": "TRAIN",
                "system": "http://terminology.hl7.org/CodeSystem/v3-ActReason",
                "display": "training"
              }
            ],
            "text": "Interoperability Testing and Training (non-clinical use)"
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        ],
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\">Provenance for SYNDERAI Synthetic Example Data Resource</div>"
        },
        "recorded": "2022-09-29T08:17:44Z"
      }
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    {
      "fullUrl": "urn:uuid:b95bbbf2-f416-45c9-a627-a8b0dd9150db",
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        "meta": {
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        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\">Laboratory Role Id: b95bbbf2-f416-45c9-a627-a8b0dd9150db</div>"
        },
        "practitioner": {
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      "fullUrl": "urn:uuid:089249b7-86b1-45b4-8d73-8083e2989f1d",
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        "resourceType": "Practitioner",
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            "value": "63b47013-4e82-4ff3-a486-6e88dbb8cc1c"
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        "name": [
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            "given": [
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            "family": "Ample"
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        ],
        "address": [
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              "Boulevard du Jardin Botanique 32"
            ],
            "postalCode": "1000",
            "city": "Brussels",
            "country": "Belgium"
          }
        ],
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\">Laboratory: Laboratoire Central Européenne, 1000 Brussels, Belgium</div>"
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      }
    }
  ],
  "type": "document",
  "timestamp": "2022-09-29T08:17:44Z"
}